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In: Health & Fitness
4 Jul 2009Resveratrol is a natural anti oxidant formed in the stem cells of the grapes and berries. Resveratrol was, firstly, discovered in the roots of Japanese knotweed. It is formed in the response to attack by bacteria or fungi. Resveratrol is the most potent anti inflammatory, anti cancer , and anti aging an agent discovered till date. Resveratrol is found in the skin of red grapes and is a constituent of red wine as well. A total amount of Resveratrol per serving of wine (a 5-ounce glass) for white wines is found to be between 0.01 to 0.27 mg.
It exists as two geometric isomers: cis (Z) and trans (E), with cis-isomer. The trans form can undergo isomerisation to the cis form when exposed to ultraviolet irradiation.
Though they can undergo isomerism, but it has been found that resveratrol is very stable in plants. Trans form is more stable even in under accelerated conditions of the 75% humidity and 40 degrees C under normal atmospheric pressure. Thus resveratrol is found stable in plants grown in the hotter climates.
The mechanisms of resveratrol’s apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calorie restriction. Resveratrol is believed to trigger SIRT1 growth hormone, which is required to stop the action of PITB in the body of a human being. Thus it helps to restrict against Diabetes Type 1 as well.
Resveratrol content has proved to be especially beneficial in the case of cancer cells. Resveratrol content interferes with all three stages of carcinogenesis” initiation, promotion and progression. Resveratrol straightaway attacks the energy source of the carcinogenic cells, mitochondria, thus stopping them from multiplying.
Resveratrol content was reported effective at neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease. Again, this has not yet been tested in humans for any disease.
